Screwball committed crimes while a camera crew filmed her. The films were placed on a web site which generated revenue based on hits. She tried to get Spider-Man on camera multiple times because "whenever you're on my show, I get more hits than ever." She and Spider-Man first encounter each other at the time when Spider-Man was tracking down the "Spider-Tracer Killer.". She posed as Spider-Man to help the Bookie by fighting a villain called Basher. The fight was uploaded on YouTube with the patrons of the Bar with No Name. The real Spider-Man showing up to stop the fight between the two of them lead to the Enforcers targeting Bookie.
She was briefly seen being chased by Spider-Girl who had informed Screwball that she was no longer broadcasting her show due to the heroine taking out her cameraman. She was last scene being arrested by the police after Spider-Girl left.
Screwball later joined forces with Jester into pranking Mayor J. Jonah Jameson. Upon uploading the prank on the Internet, both villains were defeated by Superior Spider-Man (Doctor Octopus' mind in Spider-Man's body).
Skilled in urban gymnastics.
- 25 Appearances of Screwball (Earth-616)
- 2 Minor Appearances of Screwball (Earth-616)
- Media Screwball (Earth-616) was Mentioned in
- 12 Images featuring Screwball (Earth-616)
- 3 Quotations by or about Screwball (Earth-616)
- Character Gallery: Screwball (Earth-616)
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