The third Crime Master has created his own supervillain team called the Savage Six by assembling Death Adder I, Human Fly I, Jack O'Lantern V, and Megatak upon offering them protection from the law and Kingpin. Venom was planning to take out Crime Master only to be stopped by Eddie Brock. After a fight with Venom, Jack O'Lantern discovers Eddie Brock webbed up as Crime Master forcefully bonds Eddie Brock to the Toxin symbiote. The Savage Six targets the people Venom cares about including his family and Betty Brant.
Jack O'Lantern in his human guise goes first and targets Betty Brant only to end up fighting Venom. During the fight, Megatak assists Jack O'Lantern and punches Venom's phone before he can make a call to the Avengers for help. While getting Betty away from Jack O'Lantern and Megatak, Venom is attacked by Toxin (who is in full control of Eddie Brock). Venom manages to use a sonic version of a pepper spray to immobilize Toxin before getting away.
The Savage Six soon begins to target Betty Brant's family as Betty Brant and Venom leave to go warn Betty's family. They arrive at the home of Betty's mother where they find Human Fly about to eat her. Megatak has also been monitoring the phone lines when it comes to the loved ones of Flash Thompson. Jack O'Lantern then targets Jessie Thompson and ends up fighting Venom. Venom grabs Jack O'Lantern's gun and fires on him before Jack O'Lantern spews acid on him causing Venom to cool down in the fountain. Although Venom manages to get Jessie Thompson to safety, Toxin manages to capture Betty Brant while Human Fly is eating the leftovers of what is supposedly Betty's mother. Venom continues to look for Betty and ends up killing Death Adder after ripping Human Fly's wings off to learn where Crime Master is located. When Betty is brought before Crime Master, she is shocked when the Crime Master reveals himself to be her brother Bennett Brant. When Venom arrives at Crime Master's hideout he defeats Megatak and severely burns Toxin. Bennett Brant almost kills Venom with a sonic pistol and a flamethrower, but he is shot and killed by Betty. When Venom begins to make a comment on this, Betty states that her brother "died a long time ago."
- Appear to be a darker version of the Sinister Six.
- An alternate version of the Savage Six were enemies of Spider-Girl
- 8 Savage Six (Earth-616) Members
- 6 Appearances of Savage Six (Earth-616)
- Minor Appearances of Savage Six (Earth-616)
- 1 Media Savage Six (Earth-616) was Mentioned in
- 6 Images that include Savage Six (Earth-616)
- Team Gallery: Savage Six (Earth-616)