A small, poverty stricken nation between Bolivia and Paraguay, San Domingo was virtually ruled by Hector Ramone and his drug cartel through Captain de Ortega’s military junta. The state of the country after the Punisher assassinated both men is left unclear.

Later, a team of Warheads, mercenaries who acquired advanced technology and/or magical equipment for the Mys-Tech company, gathered in San Domingo in preparation for the appearance of a wormhole.

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