Little is detailed about Leader’s life before the zombie plague arrived on Earth-2149, however it can be presumed that it followed as much of the same path as his Earth-616 counterpart.

Having becoming infected, he joined Kingpin's zombie team. When Machine Man destroyed the machines that created clones so they could feed themselves, he warned the other zombies to stop him. In the end, Machine Man killed him by burning him along with other zombies.[1]

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