Operation: Rebirth, also called Project: Rebirth, and Project: Super Soldier, is a US government project originally administered by the US Army to create a new line of Super-Soldiers for its World War II effort. It's success allowed the concept to grow and expand becoming the larger operation known as Weapon Plus.
Operation Rebirth began as a collaboration between US, British and German eugenicists led by Doctors Abraham Erskine and Koch. When World War II began, Koch took over the German program, and Erskine (under the code name of "Joseph Reinstein") became the primary source of the USA program with him independently creating both the chemical portion of the project that has been recreated to certain degrees and the Vita Ray treatment that has NOT been recreated since.
It was believed that Erskine's process would work reliably on any person which was the reason so many were dedicated to recovering Erskine's lost process. However, chemical/Vita Ray process would only be successful in 1 out of 4 participants.
The project created two failed subjects, Clinton McIntyre, a.k.a. Protocide, who was placed in suspended animation and was revived in the modern era by AIM. And the first mutant experiment the Queen who seems to have occurred prior to the serum being tested on Steve Rogers.
Erskine continued to refine the process and eventually succeeded in being able to convert frail Steven Rogers into the first Super Soldier who took the name Captain America. But Erskine was murdered moments after Rogers was successfully empowered. All of the refinements Erskine made to the program which made the process successful with Rogers, especially the Vita-Ray portion, were lost with his death as he never fully documented all of his research to the recorded notes. Though the German spy who murdered Erskine did, which was the basis of Rogers II finding and using the chemical portion of this process to become the Captain America of the 1950s.
With Erskine's murder, Wilfred Nagel took over the American program under the code name of Josef Reinstein. Nagel's attempt to recreate Erskine's successful process with Rogers, did not succeed in mass production. Nagel's early attempts to recreate Erskine's successful chemical formula resulted in African-American super soldiers (most prominently Isaiah Bradley). Three hundred African-American soldiers were taken from Camp Cathcart and subjected to potentially fatal experiments at an undisclosed location in an attempt to recreate Erskine's successful Super-Soldier Formula. Only five men survived the original trials; hundreds of test subjects left behind at Camp Cathcart and the camp's commander were executed by US soldiers in the name of secrecy, the families of the three hundred were told that they had died in battle. 
While Nagel failed to create a working mass production version of Erskine's formulae, Nagel did make relatively successful samples, such as the one that kept then Colonel Walker Price younger than his chronological age and still muscular fit into his 90s.
Although there were many later attempts to recreate or reverse-engineer Operation: Rebirth's Super-Soldier Serum in detail, none are known to have been involved with Weapon Plus except for the attempt that resulted in the creation of Isaiah Bradley's son Josiah X nor have been successful in replicating the missing Vita Ray portion. Weapon Plus considers Steven Rogers as its most successful creation.
Transportation: None known.
Weapons: None known.
- No trivia.
- 13 Operation: Rebirth (Earth-616) Members
- 4 Appearances of Operation: Rebirth (Earth-616)
- Media Operation: Rebirth (Earth-616) was Mentioned in
- 1 Images that include Operation: Rebirth (Earth-616)
- Team Gallery: Operation: Rebirth (Earth-616)
- ↑ Tales of Suspense #63
- ↑ Marvel Super-Heroes Vol 2 #3
- ↑ Captain America #109
- ↑ New X-Men #145
- ↑ Giant-Size Invaders #1
- ↑ Adventures of Captain America Vol 1
- ↑ Captain America Annual #2000
- ↑ The Spectacular Spider-Man Vol 2 #15-20
- ↑ Captain America #155
- ↑ Truth: Red, White & Black #1-7
- ↑ Amazing Spider-Man #654
- ↑ Captain America Comics #1
- ↑ Captain America #119
- ↑ Captain America #255