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Nanako was a member of the Diogenes Initiative. When a Mindless One rampaged through Las Vegas, she interrupted its fight against the Scarlet Spider and impaled it in the back, seemingly killing it. Other agents then prepared the monster for transport and they left the scene.[1]

The Scarlet Spider followed Nakano's crew and infiltrated their underground base.[1] Nakano eventually confronted him, and used the poisoned edge of her naginata to weaken him. When standing on top of the Scarlet Spider, Nakano was stopped by her boss, Gabriel.[2]




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