Due to her nephew Peter having forgotten his lunch at home, May Parker rushed to a science demonstration to give it to him. There she was bitten by a Radioactive Spider which gave her spider-like powers.
Using a costume to hide her real identity, May set out to earn money for the family doing stunts. However, when the villain Leap-Frog made an appearance, the Spider-Ma'am defeated him and became a crime fighter.
During the Great Hunt, Karn came to Earth-3123 to kill the spider-totem of this reality. May surrendered herself willingly, if only to keep her husband and nephew from harm. However, Karn was stopped by the Spider-Totems from other realities.
- 3 Appearances of May Reilly (Earth-3123)
- Minor Appearances of May Reilly (Earth-3123)
- Media May Reilly (Earth-3123) was Mentioned in
- 5 Images featuring May Reilly (Earth-3123)
- Quotations by or about May Reilly (Earth-3123)
- Character Gallery: May Reilly (Earth-3123)
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