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Joan Madrox was the mother of Jamie Madrox, who would go on to become the Multiple Man. Their family moved from Los Alamos, New Mexico to an intentionally isolated farm in Lawrenceville, Kansas at the suggestion of Professor Charles Xavier. Later, Damian Tryp Jr, of Singularity Investigations, offered to look after her son Jamie, claiming that Jamie was not in fact a mutant, but a "changeling," a predecessor to mutants whom develop their powers at birth. Jamie's parents, however, refused to give him to Tryp. She was killed in a tornado when Jamie was 15. It was later learned that tornado had been created by Tryp.
- 3 Appearances of Joan Madrox (Earth-616)
- Media Joan Madrox (Earth-616) was Mentioned in
- 2 Images featuring Joan Madrox (Earth-616)
- Quotations by or about Joan Madrox (Earth-616)
- Character Gallery: Joan Madrox (Earth-616)
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