Dr. Holden Radcliffe was a brilliant Scottish scientist and an expert in transhumanism.

He was kidnapped by Hive and forced by him to turn the Watchdogs into Inhumans. The experiment had a unknown result of creating Primitives.[1]

He later began work on an old S.H.I.E.L.D. project marked L.M.D.[2]


  • Enhanced Sight: Radcliffe replaced his right eye with a synthetic prosthesis giving him enhanced vision. This was based on the eye of a bird.[3]


Enhanced eye sight.


Dr. Radcliffe is easily able to be controlled when threatened.

  • John Hannah portrays Holden Radcliffe in the ABC series Marvel's Agents of S.H.I.E.L.D..
  • Of all the antagonists on Agents of S.H.I.E.L.D., Holden does not act out of any selfish desires. Instead, he simply wishes to ease the pain his friends have endured, albeit in a misguided way.

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