Cosmic radiation was responsible for the creation of the Fantastic Four on Reed Richards' fateful space flight. Lack of proper shielding caused Reed Richards, Sue Storm, Johnny Storm, and Ben Grimm to receive exposure to cosmic rays in space. This led to lifelong mutagenic changes in the four. It has occasionally been suggested that a higher intelligence was behind that cosmic radiation storm. 
The manipulation of cosmic rays has frequently been a part of Reed Richards's attempts to restore Ben Grimm to his human state. Reed himself used a cosmic radiation storm to recharge his own powers at a point when he had lost his elasticity. Another storm was responsible for further mutating Ben Grimm for a time, along with his partner Ms. Marvel.
Other individuals have occasionally tried to recreate the cosmic ray event in order to gain powers for themselves, with varying success. The Red Ghost and his Super-Apes and the U-Foes both succeeded in becoming cosmically empowered after the Fantastic Four.
- A solar flare caused the Van Allen radiation belts to be charged with ultra-high levels of cosmic radiation during the Fantastic Four's fateful spaceflight.
- See also: Fantastic Four #1
Cosmic Ray Enhanced Characters:
- See also: Category:Cosmic Ray Exposure
- ↑ Fantastic Four #1
- ↑ Fantastic Four #530-532
- ↑ Fantastic Four #197
- ↑ Fantastic Four #310
- ↑ Fantastic Four #13
- ↑ Incredible Hulk #254
- ↑ Hulk Vol 2 #1
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