Appearing in 1st story
Featured Characters:
- Spider-Man (Peter Parker) (Main story and flashback) (Joins the Daily Bugle)
Supporting Characters:
Antagonists:
- Unidentified burglars (First appearance) (Cameo) (Only in flashback)
- Mysterio (Quentin Beck) (First appearance) (Cameo) (Only in flashback)
- Numerous lizards (First appearance)
- Lizard (Dr. Curt Connors) (First appearance) (Main story and flashback)
Other Characters:
- Mr. Maxwell
- Flash Thompson
- Numerous unnamed New Yorkers
- U.S. Army (First appearance) (Only in flashback)
- Dan Slott (First appearance)
- Daily Bugle (Mentioned)
- J. Jonah Jameson (First appearance; photo)
- Stark Expo (Named only)
- Sandman (Flint Marko) (Photo)
- Uncle Ben Parker (Mentioned)
Races and Species:
- Humans (Main story and flashback)
Locations:
- Earth-16220 (Main story and flashback)
- Earth (Main story and flashback)
- United States of America (Main story and flashback)
- New York (Main story and flashback)
- New York City (Main story and flashback)
- Manhattan (Main story and flashback)
- Central Park (First appearance) (Main story and flashback)
- Bridge No. 24 (First appearance) (Only in flashback)
- Central Park Zoo (First appearance)
- New York City Sewer System (First appearance)
- Dr. Connors' Secret Laboratory (First appearance)
- Central Park (First appearance) (Main story and flashback)
- Queens
- Manhattan (Main story and flashback)
- New York City (Main story and flashback)
- New York (Main story and flashback)
- United States of America (Main story and flashback)
- Earth (Main story and flashback)
Items:
- Web-Shooters (Main story and flashback)
- Spider-Man's Suit (Main story and flashback)
- Spider-Man's Utility Belt (Main story and flashback)
- Spider-Man's Spider-Signal (Main story and flashback)
- Connors Formula (First appearance) (Only in flashback)
Synopsis for 1st story
- Synopsis not yet written
Solicit Synopsis
IN THE JAWS OF THE LIZARD!
• As Peter Parker finds his footing at school and with GWEN STACY…
• …SPIDER-MAN finds himself face-to-face with the LIZARD!Trivia
- Spider-Man met Lizard before the events of issue.