He was a friend of mine, you... you monster! Well, not a friend exactly. More of a nuisance, if you must know. But he was my nuisance! Prepare to-- 
Appearing in 1st story
Featured Characters:
- Deadpool (Wade Wilson) (Main story and flashback)
- ⏴ Spider-Man (Peter Parker) ⏵ (Temporarily possessed by Headmistress Soo)
Supporting Characters:
- St. Damia's students (First appearance)
- Wendy (First appearance)
- Aimee (First appearance)
- Veronica (First appearance)
- Numerous unnamed others (First appearance)
Antagonists:
- Leviathon Tide (Unnamed)
- "Eggplant" (First appearance; dies)
- Headmistress Soo (First appearance) (Temporarily possesses Spider-Man)
Other Characters:
- Queen Shiklah (Mentioned)
- Godzilla (Mentioned)
- Albert Einstein (Mentioned)
- Genghis Khan (Mentioned)
- Numerous unnamed Canadians
- Doctor Octopus (Otto Octavius) (Mentioned)
- Madcap (Mentioned)
- Avengers
- Vision (Mentioned)
- ⏴ Captain America (Sam Wilson) ⏵ (Appears on screen)
Races and Species:
- Humans (Main story and flashback)
- Succubi (Mentioned)
- Demons (Mentioned)
- Leviathons
Locations:
- Earth (Main story and flashback)
- Canada
- Toronto
- St. Damia's School for Young Women (First appearance)
- CN Tower
- Toronto
- United States of America (Appears on screen)
- Alaska (Mentioned)
- Boston, Massachusetts (Mentioned)
- Pennsylvania (Appears on screen)
- Philadelphia (Appears on screen)
- Canada
Items:
- Deadpool's Suit (Main story and flashback)
- Deadpool's Katanas (Main story and flashback)
- Spider-Armor MK IV
- Web-Shooters
- Webware
- Captain America's Uniform (Appears on screen)
Synopsis for 1st story
- Synopsis not yet written
Solicit Synopsis
A MONSTERS UNLEASHED TIE-IN!
• Spider-Man and Deadpool find themselves face-to-face(-to-face?) with one of the dozens of monsters smashing and stomping their way through the Marvel Universe!
• Ever the stalwart hero, Spider-Man has to use his powers (and responsibilities) to fearlessly fight the freakish monsters, saving many civilians at great cost to himself!
• Meanwhile, Deadpool is about as helpful as he usually is.