When Electro of Earth-449 approached Mike Dillon with the technologies for alternate universe travel, Otto Octavius, who was an employee in Mike's company was made to research this. Many alternate universe Doctors Octopi, including Young Avenger Octavia Otto, were seemingly forcibly made aid this research for the newly formed Electro-Verse. 
When the Spider-Woman, and Spider-Man of alternate universes came to free the Doctors Octopi to disable the Electro-Verse's map of the Web of Life and Destiny, the villains instantly recognised them as a Spider-Man and a Spider-Woman and began to attack them. Octavia Otto helped the Web Warriors escape the swarm of Doctors Octopi.
Equipment: Many forms of Doctor Octopus' Tentacles.
- 3 Appearances of Doctors Octopi (Earth-1082)
- Minor Appearances of Doctors Octopi (Earth-1082)
- 1 Media Doctors Octopi (Earth-1082) was Mentioned in
- 1 Images that include Doctors Octopi (Earth-1082)
- Team Gallery: Doctors Octopi (Earth-1082)