Madame Webb was a cosmic being who hailed from the same world as Beyonder. After Spider-Man was chosen by the Beyonder to participate in an ultimate battle, Madame Webb was instructed by the latter to train Spider-Man for the battle. She gave him advice when he struggled against his enemies and criminals in order for him to succeed, although Spider-Man despised her interference.
When the time came, she introduced him to the Beyonder, who placed him in a test battlefield, before assembling him into a group of Spider-Men from different realities to fight against a being named Spider-Carnage who threatened to destroy all of reality. After Spider-Carnage was defeated, Madame Webb took Spider-Man to meet his creator, Stan Lee, in another reality where he was a fictional character, and later to find the real Mary Jane Watson.
- The character was voiced by Joan Lee in Spider-Man: The Animated Series.
- 12 Appearances of Cassandra Webb (Earth-92131)
- Minor Appearances of Cassandra Webb (Earth-92131)
- Media Cassandra Webb (Earth-92131) was Mentioned in
- 3 Images featuring Cassandra Webb (Earth-92131)
- 1 Quotations by or about Cassandra Webb (Earth-92131)
- Character Gallery: Cassandra Webb (Earth-92131)
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