The issue opens up with an image of Spider-Man battling Doctor Octopus which is actually a scene from the Spider-Man film which Miles is using to hone his new found spider powers. Then Miles' Mother walks into his room wondering why he's sweating, he makes an excuse that he was working out and she notices the laptop on his bed with the Spider-Man Film. Leaving her to wonder what Miles is exactly doing. Miles begins feeling guilty about keeping his new powers and identity a secret from his parents, which is getting challenging for him and he asks himself how exactly was Peter able to keep this secret from his own parents. Now the scene changes to the Morales family at the dinner table discussing the news about an all-new Spider-Man who is currently sitting at the dinner table along with them. Miles asks his father exactly what is wrong with there being a new Spider-Man to which his father replies, "What's wrong with people running around in their underwear and trying to jump off the walls?" Miles' Father wants to move out of the city while Miles' Mother doesn't agree and tells Miles' Father to settle down. While Miles' mother thinks its cool for there to be a new Spider-Man, Miles' Father is not so happy with it because of the fact that a mutant used his powers to flood the whole city of New York causing millions of people to die, but Miles' mother reminds Miles' Father that thanks to a young boy in a Spider-Man costume, he saved countless lives and did whatever he could to save the city and also was honored after he died.
Now the scene changes to Miles hopping around rooftops practicing his new powers. Miles decides to test his wall-crawling abilities on a tall building to see how far he can climb, but soon remembers that he has a sort of fear of heights. Then Miles tries to find a way into the building so he can get downstairs, and finds himself on the hotel floor of Principal Suitress who faints in shock at seeing the new Spider-Man. Miles then hears an explosion occur far off in the distance, he decides to jump over to the area to see what is going on since he has no web-shooters yet, he cannot swing towards the danger. As Miles arrives in the area, he starts to feel a buzzing in his head which is his Spider-Sense, he starts to understand its purpose a little bit more, as he dodges a flying car that was heading right for him. He comes face to face with Omega Red, who is surprised and angered to see another Spider-Man.
The scene changes to the Tinkerer's workshop, where the Tinkerer is held at gunpoint by the Miles' uncle, the Prowler AKA Aaron Davis, who is angered by the faulty tech that Prowler provided him with. Even though the Tinkerer tells the Prowler that it is not the Tinkerer's tech that is faulty, it is the way Aaron Davis is using the tech. Then Prowler shows the Tinkerer a picture of the new Spider-Man demanding the same powers as the new Wall-Crawler thinking that the Tinkerer is responsible for the new Webhead. The Tinkerer begins to explain that the new Spider-Man is not his business and that he didn't have a hand in making him. Tinkerer then tells the Prowler about Norman Osborn and how Peter Parker obtained his spider powers making Prowler remember all about Miles getting bitten by the same spider with a number on its back, now knowing that his nephew is Spider-Man and wanting to keep it like that, he ends Tinkerer's life.
The scene then goes back to the fight between Miles and Omega Red, with Miles making fun of Omega Red's name, to quickly end the battle, Miles uses his Venom Blast which has good effect on Omega Red, putting a stop to the villain. The scene then cuts to Miles and Ganke talking about Miles fight against Omega Red and how awesome and cool the fight was. But Miles believes that in order to be prepared for much more dangerous and lethal villains he must train harder, and Ganke is about to propose an idea until Miles' Uncle Aaron appears.