Madam Web was a woman obsessed with Spider-Man, but when he rejected her she decided to get revenge by using her own spidery powers to tangle up New York Harbor in her web, knowing that he would be blamed. The love crazed fiend's plan was thwarted when Spider-Man bribed her into giving herself up and clearing both the Harbor and his good name by offering her Hostess Twinkies Cakes.
- Madam Web's one and only appearance was in an ad for Hostess Twinkies Cakes which ran in Marvel Comics dated August 1977.
- Madam Web has no known connection to Madame Web or her successor, Madame Web.
- 2 Appearances of Madam Web (Earth-616)
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