- All these souls, lost and alone, I can save them! I can cure them! There's no need to stop me, Peter!
- -- The Lizard
The Amazing Spider-Man
One of Oscorp's leading scientific minds, Dr. Curtis Connors worked with Richard Parker to engineer a revolutionary regeneration serum to help re-grow limbs and human tissue from cross-species genetics. Richard would mysteriously perish, taking with him much of his scientific genius. Connors was left unable to finish his work, effectively dooming his chances of regrowing his missing right arm.
Over a decade later, Connors is still working on the project at Oscorp, which has apparently been brought back due to the corporation's founder, Norman Osborn, being terminally ill. He also wrote a book about the possible medical breakthroughs from cross-species genetics. Under time constraints, Connors is unable to complete the project until Richard's son Peter comes into his life. Feeling guilty about cutting his close friend's son out of his life, Connors allows him to work on the project with him at Oscorp. Peter also supplies a missing algorithm from his father's notes, leading to the successful development of a serum based on lizard DNA.
Dr. Ratha, Connors' superior at Oscorp, decides to fast-track human testing. Connors pleads with him to wait until they know the full side affects, but Ratha threatens to fire him and reminds him that Richard Parker took the same stand over ten years before. Ratha decides to test the serum at the city's largest veterans' hospital. In the hopes of preventing this, Connors tries the serum on himself, turning him into the monstrous Lizard. As Curtis notices his body mutating into a reptilian form, he orders a taxi driver to drive to the Veterans hospital in hopes of stopping Dr. Ratha from injecting the serum into the patients, where they will turn into Lizards too.
Suffering from mental problems as a result of his transformation, the Lizard attempts to kill Dr. Ratha on the bridge, but is stopped by Spider-Man. After he escapes, Connors creates a makeshift lab in a sewer, in which he begins increasing the dosage of the reptilian formula. After an injection, he senses a danger. Now fully mutated, the Lizard confronts Spider-Man again, who had tracked him down into the sewer. He severely wounds the hero, but Spider-Man escapes before the finishing blow can be delivered. However, he discovers a camera marked "Property of Peter Parker", and deduces that Peter and Spider-Man are one and the same, leading to him crushing the camera.
As the dosage is increased, so does the Lizard persona. After only two injections, the Lizard has already seemingly taken a mind of its own, and begins speaking to Connors mentally. The Lizard convinces Connors to inject himself again, under the promise that he will "save" the city. Once Connors transforms, he seemingly loses control of himself, and The Lizard fully takes over.
The Lizard attacks Midtown High, looking for Peter, as he doesn't want anyone to stop what he has planned. He nearly kills Peter by causing a chemical reaction, creating a small explosive, but Peter emerges in his Spider-Man suit. During the fight, Peter tries to reason with him, but to no avail as the Lizard continues to attack him. After a lengthy battle, the police arrive, and The Lizard retreats. The Lizard then sets to work on unleashing the serum on New York City's populace via a device capable of infecting entire cities by unleashing a chemical "cloud" into the sky. On his way to OsCorp, he is attacked by a SWAT team, which he defeats easily and mutates into similar lizard-like creatures. He also transforms bystanders into lizards. Once inside OsCorp, he finds Gwen Stacy, who attempts to hide the device from him. He easily recovers the device and plants it on OsCorp tower.
As the timer counts down, Spider-Man arrives and attacks the Lizard, but is easily restrained, and Lizard destroys his web-shooters. Captain George Stacy arrives as well, and keeps the Lizard at bay by shooting him multiple times with a shotgun. Stacy gives Peter an antidote, which he replaces the reptilian formula in the device with. The Lizard murders Captain Stacy, and attempts to stop Peter. When the timer ends, a cure is released into the city, rather than the formula, curing the Lizard and all others he infected. Now reverted back into Dr. Connors, he saves Peter from falling off the OsCorp tower. In the aftermath of the crisis, Connors is incarcerated as a terrorist and is taken into a mental institution.
In the mental facility, he is visited by a shadowy figure, who demands to know if Connors told Richard's son the full story about his father. Connors says no and demands he leave Peter alone, though the man vanishes in the shadows.
During Connors' time at the asylum, Alistaire Smythe had taken over his spot at OsCorp, and planned to destroy all evidence of cross-species testing. This plan was cut short when the other cross-species mutations escaped, and began infecting New York with a "cross-species virus", which turned those infected into mindless creatures.
Spider-Man soon came to break Connors out of the asylum, knowing he was the only one who could develop a cure. Connors agreed to work on a cure, on the condition that he be taken back to the asylum after all was said and done. Peter delivered him to his current apartment, where Connors quickly began working on a cure. While Peter was out, Connors also used the credit card of Stan, a friend of the Parker family, to buy new lab equipment. When asked how much he spent, Connors replied that he just used it "until it didn't work anymore".
Connors sent Peter after a giant rat cross-species for a DNA sample, which he used to study.
Connors first attempt at a cure went horribly wrong, and ended up crippling Alistaire Smythe and driving him to insanity. Alistaire had sent a very large, snake-like S-Bot after Spider-Man as revenge, and after a very long, brutal battle, Spider-Man emerged victorious, but severely wounded. Peter returned to the apartment, concerned that the Lizard persona may be taking Connors over, and went into a rage, before passing out from his wounds. Connors soon realized that Peter, despite multiple contacts with the cross-species creatures, was never infected, and therefore, a small sample of his blood was all that was needed to perfect the cure.
The new, perfected cure was used to cure multiple scientists, including Gwen Stacy. Alistaire Smythe, however, refused to take the cure, claiming his nanobot cure would be what would save New York. In actuality, Smythe's nanobot cure was a poison, which would slowly and painfully kill it's host.
Smythe, at some point, realized Peter Parker's identity as Spider-Man, and used this knowledge to kidnap Connors, while also sending a newly developed "Spider-Slayer" after Parker. The Spider-Slayer was defeated, and Peter went to save Connors. Peter successfully saved Connors from Smythe, but ended up being captured himself.
Becoming The Lizard Once More
Connors ended up back in his makeshift lab in the sewers, in hiding for the now post-apocalyptic world New York had become under the Cross-Species outbreak. Peter eventually made his way to the lab, revealing that, while captured, Smythe had injected him with the nanobot virus, which stripped him of his powers and was slowly killing him. Realizing there was no other way, Connors was forced to become The Lizard once more, in a vain attempt to save the city.
While fighting Smythe head-on, a still powerless Spider-Man arrived. A small, electrocuted S-Bot attacked Peter, and the electricity destroyed the nanobots in him, quickly restoring his powers. Connors helped Peter defeat Smythe once and for all, before finally succumbing to the reptilian side once more, escaping into the sewers and making his way back to the lab. Peter gave chase, and eventually came to Gwen, who had rewired an S-Bot to recognize Peter as an ally. Peter used this S-Bot to track The Lizard through the sewers, now armed with the cure. The Lizard attacked, destroying the S-Bot and causing the cure to be lost in the rubble. Peter repeatedly webbed The Lizard to a wall in an attempt to search the rubble for the cure. Once he had finally found it, The Lizard made another attempt to escape. Peter came to a dead end, before The Lizard appeared through metal bars and dragged him into another room. After a lengthy battle, Peter subdued The Lizard and gave Connors the cure. Connors' cure was used to cure the rest of the city, and Peter expressed that "Today, The Lizard was a hero".
The manual in the Amazing Spider-Man video game states that the Lizard killed Dr. Ratha, despite this not being seen in the movie. It is, however, supported by screenshots and clips taken from some of the film's trailers, which hint at a deleted scene where Ratha, Connors, and Peter meet in the Lizard's sewer lair just prior to the climactic race to Oscorp. Dialogue between Ratha and Peter are prominent in the film's trailer, despite the two never meeting in the finished cut.
- 3 Appearances of Curtis Connors (Earth-120703)
- 4 Images featuring Curtis Connors (Earth-120703)
- 1 Quotations by or about Curtis Connors (Earth-120703)
- Character Gallery: Curtis Connors (Earth-120703)
- Fan-Art Gallery: Curtis Connors (Earth-120703)
- Characters killed by Lizard
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