In Las Vegas, the demonic son of Mephisto, Blackheart opened a portal to bring Hell to Earth and overthrow his father, but only managed to bring a part of it. Venom was a fugitive there, with Red Hulk wanting to bring him to the authorities. X-23 was there looking for who stole a sample of her blood. And the new Ghost Rider detected Blackheart's malevolence. Accidentally, the four heroes found themselves about to battle Blackheart.
The villain created Anthiteses of the four heroes to battle and torment them, Flash's being an Evangelist who used the symbiote, his father and his drinking problem to fight him. Although the heroes battled well, they were ultimately killed. Flash's neck was snapped by Blackheart's girlfriend Gari Oyle after he murdered the Evangelist. In Hell, Mephisto offered the heroes a new chance to live in exchange for defeating Blackheart. They managed to get the Spirit of Vengeance, which had been trapped by Blackheart, and wanted to get it to Blaze, so he would become Ghost Rider again. During the battle, Red Hulk and Venom were thrown away by Blackheart. Flash gave the symbiote to Red Hulk and it bonded with him as well as the Spirit, thus becoming the new Ghost Rider.
Blackheart was defeated when Ghost Rider used a mirror which creates Antithesis, being defeated by his. Meanwhile, Flash and X-23 were trying to help Johnny Blaze to return Hell from the dimensional portal and destroy it. When Las Vegas returned to normal, Red Hulk returned the symbiote to Flash and the Spirit of Vengeance to Alejandra, and she left the scene. When the Secret Avengers arrived, Captain America tried to take Venom to custody, but he convinces Cap to let him join the Secret Avengers, allowing Giant-Man and Beast to try to make the symbiote more controllable.
Issues in the story arc have not been added.
- The main protagonists of the event are a homage to the New Fantastic Four, Venom mirroring Spider-Man, Red Hulk mirroring Hulk/Mr. Fixit, X-23 mirroring Wolverine, and Ghost Rider (Alejandra Blaze) mirroring Ghost Rider (Danny Ketch). Although these heroes never created a formal alliance as a team.
- Venom Vol 2 #13
- Venom Vol 2 #13.1
- Venom Vol 2 #13.2
- Venom Vol 2 #13.3
- Venom Vol 2 #13.4
- Venom Vol 2 #14