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Brandon Chambers was a scientist[1] and executive for Roxxon Energy Corporation.[2][1][3] He recruited his brother Phillip, a better scientist expert in DNA-splicing, to work for Roxxon in a project to create ad-hoc hybrids.[2] Brandon led the project for Roxxon, answering to a Mr. Greycrest. Phillip told Brandon that their brother Mitchell had died due to cancer,[2] but really Phillip had used Mitchell as a test subject and turned him into a monster[2][4]

When the project was advanced, Brandon and Phillip decided to escape from Roxxon and sold it to more profitable, and even less ethical, underworld interests.[2] Their plan was stopped by Spider-Man, Punisher and Sabretooth; Sabretooth killed Phillip[2][4] but not before Phillip revealed that Mitchell had been turned into a monster.[2] Spider-Man and the Punisher exposed the illegal operation,[2][1] but Brandon captured Mitchell and offered it to Roxxon to have more funds for his own trial.[2]

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